Please, add rule to clear “c:\Users\***\AppData\Roaming\Skype\***\media_messaging\media_cache_v3\” folder. Too many small files, really annoying defragmentation.
i think your example is: (but im not sure if it works, you have test it yourself. PS: use at your own risk)
[Your Custom Skype rule*]
LangSecRef=3022
Detect=HKCU\Software\Skype
DetectFile=%ProgramFiles%\Skype For Salesforce
Default=False
FileKey1=%AppData%\Skype\*\media_messaging\media_cache_v3|*.*
Have a nice day